If you can afford this device, somehow, get it. I have PMDD and to say my mood swings are now night and day (almost not there during luteal) is shocking even to write. Use it every day in... Voir plus
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If you can afford this device, somehow, get it. I have PMDD and to say my mood swings are now night and day (almost not there during luteal) is shocking even to write. Use it every day in... Voir plus
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I’ve just finished the second cycle with Nettle, and OH MY GOD?! I don’t remember the last time when I’ve had energy through the whole month and not just the first 10 days of the cycle. There were st... Voir plus
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I had a full hysterectomy several years ago. So I can't speak on how well Lutea works on menstrual. But as for the mental brain fog and anxiety issues it has helped greatly. I feel calmer and able to... Voir plus
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The Nettle has been life changing as someone with pcos and pmdd, and long term depression. It’s helped me to manage my mood and reduced my pain symptoms. It’s not like any other treatment I have exper... Voir plus
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Samphire Neuroscience is a neurotechnology company dedicated to maximizing the wellbeing of women by delivering pioneering neurotechnology and evidence-based solutions that are drug and hormone-free. Our products include Nettle™, a medically-approved brain stimulation device to tackle PMS and menstrual pain non-invasively, Lutea™, a wellness brain stimulation device to support women during hormonally challenging moments, and the Samphire App, which helps women understand the patterns behind their cycles.
85 Great Portland Street, W1W 7LT, London, Royaume-Uni
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I use Nettle since January and after a few problems I found my rhythm of using and it helps a lot with my symptoms. I also have adhd and I‘m autistic and I have the feeling, that nettle makes me calmer. The best thing of nettle are the people behind it. The Team is so fantastic and passionate.

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Nettle has been such a welcome addition to my PMDD treatment. I love that this has been designed and made by women, for people who are often forgotten by our patriarchal medical systems. Firstly, the team go above and beyond – the care and support is next level, it’s personalised, it’s prompt and I trust the team want the best for me. I do multiple things to manage my PMDD, so it’s hard to pin down the effect of individual treatments, however I can say this has definitely helped raise the floor and level out the extreme drops. Sometimes when I’m having good month and use Nettle anyway, I feel more energised and alert. It’s also a good comfort-blanket to know I have something science-backed and non-invasive whenever I need it. I love that the app gets updated from us, the community. I’ve had a couple of suggestions implemented and that feels wonderful to be part of! No big-pharma or tech-bros over here. Love your work team ❤️

Réponse de Samphire Neuroscience
My experience wasn't smooth from the beginning. I wasn't able to connect Nettle with my personal smartphone. It only worked with other smartphone. And the app itself acts very strange, one time all texts and images/videos are visible, other time no images/videos visible and even text on buttons are not fully visible, it is happening when trying to run session with instruction step by step. Also resently Nettle starts not turning on even it was charged over the night. And I was needed to recharge it again. And next day it is happening again I need to recharge to be able start a session.
I still have hope that it will help me. It is only two cycles of period past, so I can't say if it is really helping. Maybe the mood is better. But still no affection to pain strenght.

Réponse de Samphire Neuroscience
I suffer from PMDD and Nettle has been a lifesaver for me! For 2 weeks of every month I used to suffer from extreme anxiety and depression that was debilitating. Since using Nettle my symptoms are so much more manageable. It’s really helped me when I felt I was running out of options. Also, the team that run it are amazing people, they are always there to answer any questions you may have and you can tell they really care! Cannot recommend this product enough!

Réponse de Samphire Neuroscience
Since joining Samphire and getting the Nettle headband, my life has changed so much. I suffer with PMDD and my periods can vary however since using Nettle, I have seen a significant decrease in physical and mental symptoms and it’s not half as bad as what it’ll my symptoms could be. I’m still quite new to nettle but I honestly won’t ever go without it. Thank you so much to the team at Samphire.

Réponse de Samphire Neuroscience
Nettle has completely transformed my life. My PMDD symptoms are significantly reduced and whilst not completely gone, what felt like drowning in a storm now feels like navigating it in a pretty sturdy ship.
I feel like I have more control over my symptoms, I’m able to do more of the things that I do outside of luteal phase, and I have more mental clarity. Instead of my cycle feeling like two opposite ends of the spectrum, it now feels more balanced and less like I have to spend the first week of my cycle recovering from luteal the week before.
Thank you so much Samphire Neuroscience. I discovered Nettle through a Queen Mary University trial and I hope one day for all people who experienced PMDD that it will be available on the NHS. It truly has changed my life

Réponse de Samphire Neuroscience
Samphire is a startup exactly as it should be: delivering an innovative and truly needed product in the way customers actually need it. They stay close, listen carefully to feedback and respond quickly whenever improvements are required.
I’m very satisfied with both the product and the service — highly recommended!

Réponse de Samphire Neuroscience
Absolutely life changing device. I have seen such a difference in my symptoms since using this. Less pain, fewer mental health concerns. Customer service has been impeccable.

Réponse de Samphire Neuroscience
Amazing customer service and support. Nettle has helped with my PMDD symptoms and would highly recommend it to others.

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I have now been using Nettle for over a year and it is life changing.
PMDD symptoms are vastly reduced.
It is very easy to use, I have very thick hair and it hasn’t been an issue.
Customer service are very responsive and were very helpful when I had charging issues.

Réponse de Samphire Neuroscience
I’m one of the early buyers of the Nettle neurostimulation headband in France, and I’ve been using it since the very beginning. I can honestly say it has completely changed the way I experience my period.
I used to have extremely painful periods — the kind that forced me to take painkillers every single month since my very first cycle. I’m 30 now, and since I started using Nettle, I haven’t taken a single painkiller. For me, that alone is absolutely huge. Some months my pain goes down to almost zero, and even on the more difficult ones, it’s still nothing compared to what I used to go through.
For mood regulation, I didn’t notice a major improvement. However, knowing that my pain will be low or manageable has removed a lot of the fear and anxiety I used to feel before my cycle. That in itself has made the whole experience emotionally easier.
I also noticed that my period flow has become much lighter — I can’t say for sure if this is related to Nettle, but it has been consistent since I started using it.
I have experienced ongoing technical issues with the device and had to send it back multiple times. But the Samphire team has always been incredibly responsive and helpful. They answered quickly, guided me through the process, and always found a solution. Their customer service really stands out.
Even with the technical problems, I genuinely believe this headband has drastically changed my life, and I truly wish it could be known and accessible to every woman who struggles with period pain.

Réponse de Samphire Neuroscience
Most incredible decision I have made to support my health. My pain is much more manageable, my quality of life has improved drastically. Also, the customer support is out of this world. I recommend this to everyone I believe it could be useful for. Incredible 100/10!

Réponse de Samphire Neuroscience
Using a Nettle has changed my life. The week before my period, are now doable.
Before Nettle, I felt overwhelmed, anxious and even angry the week before my period. Now that's replaced with a bit of tiredness and most importantly my happiness stays throughout my cycle.
This headband is an absolute game changer!! I am literally recommending it to any woman, who deals with an overwhelming luteal phase.
Thank you so much Samphire Neuroscience, everyone I have been in contact with has been so helpful and kind.

Réponse de Samphire Neuroscience
This is truly one of the most honest and amazing companies out there. Their customer service goes above and beyond every time. You can really feel that they operate with integrity and strong ethics. Also — the headband works amazing!

Réponse de Samphire Neuroscience
I subscribed to the Samphire app to see phase-based suggestions I can act on. However, I didn’t find a strong “wow” factor to continue the subscription because most period-tracking apps already offer similar features like predicting periods, tracking symptoms across phases, and explaining what’s happening in the body during each phase.
But my question is: What am I supposed to actually do with these tracked experiences? I already know that I’ll go through certain physical and emotional patterns in each phase. If there are no actionable insights, habits, or real behavior guidance based on the data, then simply tracking what I already know doesn’t feel meaningful or useful.
The app also has sleep and step goal tracking for each phase, which is a nice idea, but I’m confused about how it’s calculating these metrics. There was no prompt to connect a smartwatch or any external device, and I’m not able to see the tracked metrics in the app. I feel like the data isn’t actually being collected, or I’m missing something. If the app relies on a wearable device, it should clearly ask for it. Right now, I’m left unsure about how these goals are being measured.

Réponse de Samphire Neuroscience
After about 1/2 year, my Nettle is still working and I keep feeling better! Especially my mood in the second half of my cycle - it is not only „less instable“, but genuinely happy! Also, the App is improving continuously.
The only problem is the price of the delivery to germany (of the refills). 18 Euros. That’s too much, but I guess we have to thank Brexit for that, not Samphire Neuroscience. They reacted immediately and now allow for 3 refill packages to be purchased at the same time! Love the service!
It’s the product that counts and it does make a huge difference in my life!
Thank you!

Réponse de Samphire Neuroscience
I have had a wonderful three months so far. The Nettle headband has helped with my cramps and my PMDD extreme emotions. The app that you use along with it has meditation for each phase of your period. It also let's you log all of your emotions, over or under eating, really anything that you associate with your menstrual cycle. The longer you use it and the more often you log things the more info it has to show you how you are really feeling and doing. You can compare the changes over the months easily. The people that work at the company and I think the founder are so responsive and helpful with every question and issue that I have had. I really love this company. It is weird to say I feel seen and cared for by them. I just don't think I have felt like this with any other business.

Réponse de Samphire Neuroscience
I used Nettle for four full cycles and was honestly surprised by how much it helped. My PMS symptoms—especially the fatigue, brain fog, and low mood—improved so much. I felt more balanced and clearer in the days before my period, which had not been the case for a long time. My pain also got better: I took less medication overall, and it worked faster when I did need it.
Generally, I think it might take more than four months to see the full effect, especially for pain, but what I did experience was already a big shift. The 90-day trial (and the extra time I was offered) made it feel safe to give it a proper try, and I really appreciated that.
The customer service is genuinely some of the best I have come across—kind, quick to reply, and clearly invested in helping people feel better.
So overall, I highly recommend this product - I really wish I had had this two years ago!

Réponse de Samphire Neuroscience
Nettle is very expensive and so I was skeptical that it would be worth it. I have used it for two cycles now. This is not a lot of data to compare, but both of these periods have been a lot easier to deal with than my usual ones - less pain, but more importantly, I didn't really experience much PMS/bad moods/mood swings in the preceeding days like I usually did. I am pleased with the purchase and would recommend. My only downside is that the app is a bit unclear about the protocols - it says "consistency is key" but I don't know if that means "use at exactly the same time every day" or just means "use it every day" for the five days before your period (in my case).

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Réponse de Samphire Neuroscience
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